| Weight | 440.95 g/mol |
|---|---|
| Formula | C24H26ClFN4O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 5 |
SERTINDOLE (106516-24-9)
Score:
#119 in Neurology
,
#551 in Neuroscience
,
#2484 in Biology
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#3099 in Chemistry
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- Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertindole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials (Schizophrenia Research, 1999)
- Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia (American Journal of Psychiatry, 1997)
- The Antipsychotic Agent Sertindole is a High Affinity Antagonist of the Human Cardiac Potassium Channel HERG (Journal of Pharmacology and Experimental Therapeutics, 1998)
- A randomized, controlled, dose-ranging trial of sertindole in patients with schizophrenia (Psychopharmacology, 1996)
- Effects of newer atypical antipsychotics on autonomic neurocardiac function : A comparison between amisulpride, olanzapine, sertindole, and clozapine (Journal of Clinical Psychopharmacology, 2001)
- Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics. (Neuropsychopharmacology, 2008)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O
-
InChIKeyGZKLJWGUPQBVJQ-UHFFFAOYSA-N
- Pubchem - SERTINDOLE
- Wikipedia - sertindole
Sertindole (brand names: Serdolect and Serlect) is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company Lundbeck and marketed under license by Abbott Labs. Like other atypical antipsychotics, it has activity at dopamine and serotonin receptors in the brain.
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SCHEMBL7332496
(Reductive amination)
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SERTINDOLE
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