Weight | 279.855 g/mol |
---|---|
Formula | C17H26ClN |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
sibutramine (106650-56-0, 84485-00-7)
Score:
#233 in Neuroscience
,
#1080 in Biology
,
#1214 in Chemistry
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- Effect of sibutramine on weight maintenance after weight loss: a randomised trial* (The Lancet, 2000)
- Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects (The New England Journal of Medicine, 2010)
- Drug treatments for obesity: orlistat, sibutramine, and rimonabant (The Lancet, 2007)
- Sibutramine produces dose-related weight loss. (Obesity Research, 1999)
- Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine (The American Journal of Medicine, 1999)
- Behavior Therapy and Sibutramine for the Treatment of Adolescent Obesity: A Randomized Controlled Trial (JAMA, 2003)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C
-
InChIKeyUNAANXDKBXWMLN-UHFFFAOYSA-N
- Pubchem - sibutramine
- Wikipedia - sibutramine
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. Until 2010, it was widely marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions including Australia, Canada, China, the European Union, Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom, and the United States.
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