| Weight | 409.82 g/mol |
|---|---|
| Formula | C19H18ClF2N3O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Sitafloxacin (163253-35-8, 127254-12-0)
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- In Vitro Activities of Sitafloxacin (DU-6859a) and Six Other Fluoroquinolones against 8,796 Clinical Bacterial Isolates (Antimicrobial Agents and Chemotherapy, 2000)
- A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity (British Journal of Dermatology, 2003)
- Comparative in vitro antimicrobial activities of the newly synthesized quinolone HSR-903, sitafloxacin (DU-6859a), gatifloxacin (AM-1155), and levofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex (Antimicrobial Agents and Chemotherapy, 1999)
- Synthesis, biodistribution and evaluation of 99mTc-sitafloxacin kit: a novel infection imaging agent (Journal of Radioanalytical and Nuclear Chemistry, 2010)
- Sitafloxacin and Garenoxacin May Overcome the Antibiotic Resistance of Helicobacter pylori with gyrA Mutation (Antimicrobial Agents and Chemotherapy, 2009)
- Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae (Journal of Antimicrobial Chemotherapy, 2008)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1CC12CN(CC2N)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)C5CC5F)F
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InChIKeyPNUZDKCDAWUEGK-UHFFFAOYSA-N
- Pubchem - Sitafloxacin
- Wikipedia - Sitafloxacin
Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.
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