| Weight | 290.404 g/mol |
|---|---|
| Formula | C14H30N2O4+2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 9 |
succinylcholine (306-40-1, 71-27-2)
Score:
#347 in Neuroscience
,
#1583 in Biology
,
#1859 in Chemistry
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- Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. (Anesthesiology, 1993)
- Pathophysiology of hyperkalemia induced by succinylcholine. (Anesthesiology, 1975)
- Succinylcholine -induced hyperkalemia in acquired pathologic states : Etiologic factors and molecular mechanisms (Anesthesiology, 2006)
- Critical Hemoglobin Desaturation Will Occur before Return to an Unparalyzed State following 1 mg/kg Intravenous Succinylcholine (Anesthesiology, 1997)
- Rocuronium versus succinylcholine for rapid sequence induction intubation. (Cochrane Database of Systematic Reviews, 2015)
- Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine (Pharmacology & Therapeutics, 1990)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
-
InChIKeyAXOIZCJOOAYSMI-UHFFFAOYSA-N
- Pubchem - succinylcholine
- Wikipedia - succinylcholine
Suxamethonium chloride, also known as suxamethonium or succinylcholine, is a medication used to cause short-term paralysis as part of general anesthesia. This is done to help with tracheal intubation or electroconvulsive therapy. It is given either by injection into a vein or muscle.
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Synthesis
Reactant
+
choline
(O-acylation)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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