| Weight | 411.469 g/mol |
|---|---|
| Formula | C23H21N7O |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 4 |
TASOSARTAN (145733-36-4)
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- Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding. (Journal of Pharmacology and Experimental Therapeutics, 2000)
- Metabolites of the Angiotensin II Antagonist Tasosartan: The Importance of a Second Acidic Group (Journal of Medicinal Chemistry, 1998)
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial of Four Doses of Tasosartan in Patients With Essential Hypertension (American Journal of Hypertension, 1998)
- Effects of angiotensin antagonism with tasosartan on regional and systemic haemodynamics in hypertensive patients (Journal of Hypertension, 1998)
- Efficacy and tolerability of tasosartan, a novel angiotensin II receptor blocker: Results from a 10-week, double-blind, placebo-controlled, dose-titration study (American Heart Journal, 1999)
- Tolerability profile of tasosartan, a long-acting angiotensin II AT1 receptor blocker, in the treatment of patients with essential hypertension (Current Therapeutic Research-clinical and Experimental, 1997)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCC1=C2CCC(=O)N(C2=NC(=N1)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
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InChIKeyADXGNEYLLLSOAR-UHFFFAOYSA-N
- Pubchem - TASOSARTAN
- Wikipedia - tasosartan
Tasosartan is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.
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