| Weight | 499.714 g/mol |
|---|---|
| Formula | C26H45NO6S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 7 |
TAUROCHENODEOXYCHOLIC ACID (516-35-8)
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- Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat (Gastroenterology, 1998)
- 6-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes (Biochimica et Biophysica Acta, 1999)
- Enzymic Studies of Bile Acid Metabolism I. 6-HYDROXYLATION OF CHENODEOXYCHOLIC AND TAUROCHENODEOXYCHOLIC ACIDS BY MICROSOMAL PREPARATIONS OF RAT LIVER (Journal of Biological Chemistry, 1968)
- Effects of Acute Administration of Taurocholic and Taurochenodeoxycholic Acid on Biliary Lipid Excretion in the Rat (Experimental Biology and Medicine, 1976)
- Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers (American Journal of Physiology-gastrointestinal and Liver Physiology, 2005)
- Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats (International Immunopharmacology, 2011)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(CCC(=O)NCCS(=O)(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
-
InChIKeyBHTRKEVKTKCXOH-UHFFFAOYSA-N
- Pubchem - TAUROCHENODEOXYCHOLIC ACID
- Wikipedia - taurochenodeoxycholic acid
Taurochenodeoxycholic acid is a bile acid formed in the liver of most species, including humans, by conjugation of chenodeoxycholic acid with taurine. It is secreted into bile and then into intestine. It is usually ionized at physiologic pH, although it can be crystallized as the sodium salt.
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