| Weight | 200.169 g/mol |
|---|---|
| Formula | C8H9FN2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
tegafur (82294-77-7, 17902-23-7)
Ftorafur · FT 207 · 1-(Tetrahydro-2-furanyl)-5-fluorouracil
Score:
#1508 in Biochemistry
,
#3520 in Biology
,
#4412 in Chemistry
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- A Randomized Trial of Adjuvant Chemotherapy with UracilTegafur for Adenocarcinoma of the Lung (The New England Journal of Medicine, 2004)
- Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients. (European Journal of Cancer, 1998)
- Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer : The Japan Clinical Oncology Group Study (JCOG9205) (Journal of Clinical Oncology, 2003)
- Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and X rays (International Journal of Radiation Oncology Biology Physics, 1982)
- Antitumor Activity of 1 m Tegafur-0.4 m 5-Chloro-2,4-dihydroxypyridine-1 m Potassium Oxonate (S-1) against Human Colon Carcinoma Orthotopically Implanted into Nude Rats (Cancer Research, 1996)
- Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. (Journal of Clinical Oncology, 2002)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ftorafur
- FT 207
- 1-(Tetrahydro-2-furanyl)-5-fluorouracil
- FT207
- Fluorofur
- 1-(2-Tetrahydrofuryl)-5-fluorouracil
- Bristol-Myers Squibb Brand of Tegafur
- FT-207
- Florafur
- 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
- Utefos
- Futraful
- Uftoral
- Bristol Myers Squibb Brand of Tegafur
- Sunfural S
- Prasfarma Brand of Tegafur
- Almirall Brand of Tegafur
- N1-(2'-Tetrahydrofuryl)-5-fluorouracil
-
SMILESC1CC(OC1)N2C=C(C(=O)NC2=O)F
-
InChIKeyWFWLQNSHRPWKFK-UHFFFAOYSA-N
- Pubchem - tegafur
- Wikipedia - tegafur
Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers. It is a component of the combination drug tegafur/uracil. When metabolised, it becomes 5-FU.
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