Weight | 624.874 g/mol |
---|---|
Formula | C38H52N6O2 |
Hydrogen Acceptors | 8 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 6 |
Tirilazad (110101-66-1)
Score:
#224 in Neurology
,
#1026 in Neuroscience
,
#4469 in Biology
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- Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial (JAMA, 1997)
- Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. (JAMA, 1997)
- Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up Results of the third National Acute Spinal Cord Injury randomized controlled trial (Journal of Neurosurgery, 1998)
- Randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in Europe, Australia, and New Zealand. (Journal of Neurosurgery, 1996)
- A multicenter trial on the efficacy of using tirilazad mesylate in cases of head injury. (Journal of Neurosurgery, 1998)
- A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America (Journal of Neurosurgery, 1997)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CC2C3CCC4=CC(=O)C=CC4(C3=CCC2(C1C(=O)CN5CCN(CC5)C6=NC(=NC(=C6)N7CCCC7)N8CCCC8)C)C
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InChIKeyRBKASMJPSJDQKY-UHFFFAOYSA-N
- Pubchem - Tirilazad
- Wikipedia - tirilazad
Tirilazad is a drug that has been proposed to treat acute ischaemic stroke. When tested on animal models, tirilazad protects brain tissue, and reduces brain damage. However, the drug fails to treat, and even worsens a stroke when studied on a human being.
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