| Weight | 133.194 g/mol |
|---|---|
| Formula | C9H11N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
tranylcypromine (3721-26-4, 155-09-9)
Parnate · Tranylcypromine Sulfate · Jatrosom
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#343 in Neuroscience
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#1563 in Biology
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#1831 in Chemistry
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- Pharmacotherapy of Borderline Personality Disorder: Alprazolam, Carbamazepine, Trifluoperazine, and Tranylcypromine (Archives of General Psychiatry, 1988)
- Tranylcypromine versus imipramine in anergic bipolar depression. (American Journal of Psychiatry, 1991)
- Parachlorophenylalanine reversal of tranylcypromine effects in depressed patients. (Archives of General Psychiatry, 1976)
- Tranylcypromine Versus Venlafaxine Plus Mirtazapine Following Three Failed Antidepressant Medication Trials for Depression: A STAR*D Report (American Journal of Psychiatry, 2006)
- Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2 (Journal of the American Chemical Society, 2010)
- The effects of putative 5-hydroxytryptamine antagonists on the behaviour produced by administration of tranylcypromine and L-tryptophan or tranylcypromine and L-DOPA to rats. (British Journal of Pharmacology, 1978)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Parnate
- Tranylcypromine Sulfate
- Jatrosom
- Transamine
- trans-2-Phenylcyclopropylamine
- trans 2 Phenylcyclopropylamine
-
SMILESC1C(C1N)C2=CC=CC=C2
-
InChIKeyAELCINSCMGFISI-UHFFFAOYSA-N
- Pubchem - tranylcypromine
- Wikipedia - tranylcypromine
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate) is a monoamine oxidase inhibitor (MAOI); more specifically, tranylcypromaine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. Tranylcypromine is a propylamine formed from the cyclization of amphetamine's side chain; therefore, it is classified as a substituted amphetamine.
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