| Weight | 320.309 g/mol |
|---|---|
| Formula | C13H16N6O4 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 2 |
Triciribine (35943-35-2)
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- Phase I-II study: triciribine (tricyclic nucleoside phosphate) for metastatic breast cancer (Cancer Chemotherapy and Pharmacology, 1995)
- Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia (Journal of Cellular Physiology, 2011)
- Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT (Investigational New Drugs, 2011)
- Activity of triciribine and triciribine-5'-monophosphate against human immunodeficiency virus types 1 and 2 (AIDS Research and Human Retroviruses, 1993)
- The Akt inhibitor triciribine sensitizes prostate carcinoma cells to TRAIL-induced apoptosis (International Journal of Cancer, 2009)
- Dual Mechanisms of Inhibition of DNA Synthesis by Triciribine (Cancer Research, 1990)
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SMILESCN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N
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InChIKeyHOGVTUZUJGHKPL-UHFFFAOYSA-N
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