| Weight | 266.341 g/mol |
|---|---|
| Formula | C14H22N2O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
TRIMETAZIDINE (5011-34-7)
Centrophne · Trimtazidine Irex · Irex Brand of Trimetazidine Dihydrochloride
Score:
#1456 in Biochemistry
,
#3447 in Biology
,
#4302 in Chemistry
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- The Antianginal Drug Trimetazidine Shifts Cardiac Energy Metabolism From Fatty Acid Oxidation to Glucose Oxidation by Inhibiting Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase (Circulation Research, 2000)
- Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Trimetazidine European Multicenter Study Group. (British Journal of Clinical Pharmacology, 1994)
- Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure (European Heart Journal, 2005)
- A Randomized Clinical Trial of Trimetazidine, a Partial Free Fatty Acid Oxidation Inhibitor, in Patients With Heart Failure (Journal of the American College of Cardiology, 2006)
- Trimetazidine, a Metabolic Modulator, Has Cardiac and Extracardiac Benefits in Idiopathic Dilated Cardiomyopathy (Circulation, 2008)
- Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy (American Heart Journal, 2003)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Centrophne
- Trimtazidine Irex
- Irex Brand of Trimetazidine Dihydrochloride
- Vastarel
- Biopharma Brand of Trimetazidine Dihydrochloride
- Trimetazidine Dihydrochloride
- Idaptan
- Alpharma Brand of Trimetazidine Dihydrochloride
- Danval Brand of Trimetazidine Dihydrochloride
- Vasartel
-
SMILESCOC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC
-
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- Pubchem - TRIMETAZIDINE
- Wikipedia - trimetazidine
Trimetazidine is a drug for angina pectoris sold under many brand names. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of fatty acid metabolism, also known as fatty acid oxidation inhibitor.
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MolPort-028-959-507
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TRIMETAZIDINE
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