Weight | 438.011 g/mol |
---|---|
Formula | C27H32ClNO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 10 |
TRIPARANOL (78-41-1)
MER 29 · MER-29 · MER29
Score:
#2377 in Biochemistry
,
#4699 in Biology
,
#5966 in Chemistry
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- Reversal of Acquired Resistance to Doxorubicin in P388 Murine Leukemia Cells by Tamoxifen and Other Triparanol Analogues (Cancer Research, 1984)
- Studies of cholesterol biosynthesis. I. The identification of desmosterol in serum and tissues of animals and man treated with MER-29. (Journal of Biological Chemistry, 1960)
- Specific inhibition of cholesterol biosynthesis by a synthetic compound (MER-29) (Archives of Biochemistry and Biophysics, 1959)
- Cataracts in Patients Treated with Triparanol (JAMA, 1962)
- Triparanol inhibition of Tetrahymena, and its prevention by lipids (Archives of Biochemistry and Biophysics, 1962)
- The skin sterols of normal and triparanol-treated rats* (Journal of Lipid Research, 1963)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - MER 29
- MER-29
- MER29
- Metasqualene
-
SMILESCCN(CC)CCOC1=CC=C(C=C1)C(CC2=CC=C(C=C2)Cl)(C3=CC=C(C=C3)C)O
-
InChIKeySYHDSBBKRLVLFF-UHFFFAOYSA-N
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Synthesis
Diethyl(2-phenoxyethyl)amine
+
Reactant
(Friedel-Crafts alkylation)
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