| Weight | 609.743 g/mol |
|---|---|
| Formula | C37H41N2O6+ |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 2 |
tubocurarine
Tubocurarine Chloride · Tubocurare · d-Tubocurare
6989-98-6, 57-94-3, 57-95-4, 8063-06-7
Score:
#365 in Neuroscience
,
#550 in Biochemistry
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#1665 in Biology
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#1963 in Chemistry
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- Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. (Clinical Pharmacology & Therapeutics, 1979)
- Determinants of Apamin and d-Tubocurarine Block in SK Potassium Channels (Journal of Biological Chemistry, 1997)
- d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor (Proceedings of the National Academy of Sciences of the United States of America, 1990)
- Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80coated polybutylcyanoacrylate nanoparticles: An in situ brain perfusion study (Journal of Microencapsulation, 1998)
- Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by Torpedo postsynaptic membranes: stoichiometry and ligand interactions. (Biochemistry, 1979)
- THE EFFECT OF TUBOCURARINE ON INDIRECTLY ELICITED TRAIN-OF-FOUR MUSCLE RESPONSE AND RESPIRATORY MEASUREMENTS IN HUMANS (BJA: British Journal of Anaesthesia, 1975)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tubocurarine Chloride
- Tubocurare
- d-Tubocurare
- d-Tubocurarine
-
SMILESCN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC(=C(C=C7)O)O3)[N+](CCC6=CC(=C5O)OC)(C)C)OC
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InChIKeyJFJZZMVDLULRGK-UHFFFAOYSA-O
- Pubchem - tubocurarine
- Wikipedia - tubocurarine
Tubocurarine (also known as d-tubocurarine or DTC) is a toxic alkaloid historically known for its use as an arrow poison. In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is now rarely used as an adjunct for clinical anesthesia because safer alternatives, such as cisatracurium and rocuronium, are available.
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