Weight | 143.23 g/mol |
---|---|
Formula | C8H17NO |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 4 |
VALNOCTAMIDE (4171-13-5)
2-ethyl-3-methylpentamide · valmethamide
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- Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid (Epilepsy Research, 1998)
- Stereoselective pharmacokinetic analysis of valnoctamide in healthy subjects and in patients with epilepsy (Clinical Pharmacology & Therapeutics, 1997)
- Valnoctamide as a valproate substitute with low teratogenic potential in mania: a double-blind, controlled, add-on clinical trial (Bipolar Disorders, 2010)
- Pharmacokinetics of a valpromide isomer, valnoctamide, in healthy subjects (European Journal of Clinical Pharmacology, 1990)
- Disposition of valpromide, valproic acid, and valnoctamide in the brain, liver, plasma, and urine of rats. (Drug Metabolism and Disposition, 1996)
- Pharmacokinetic-Pharmacodynamic Relationships of (2S,3S)-Valnoctamide and Its Stereoisomer (2R,3S)-Valnoctamide in Rodent Models of Epilepsy (Pharmaceutical Research, 2003)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2-ethyl-3-methylpentamide
- valmethamide
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SMILESCCC(C)C(CC)C(=O)N
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InChIKeyQRCJOCOSPZMDJY-UHFFFAOYSA-N
- Pubchem - VALNOCTAMIDE
- Wikipedia - valnoctamide
Valnoctamide (INN, USAN) has been used in France as a sedative-hypnotic since 1964. It is a structural isomer of valpromide, a valproic acid prodrug; unlike valpromide, however, valnoctamide is not transformed into its homologous acid, valnoctic acid, in vivo.
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