| Weight | 383.47 g/mol |
|---|---|
| Formula | C17H25N3O5S |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 8 |
VERALIPRIDE (66644-81-3)
Agral · N-(1-allyl-2-pyrrolidinyl)methyl-2,3-dimethoxy-5-sulfamoylbenzamide · Veraligral
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- A double-peak phenomenon in the pharmacokinetics of veralipride after oral administration: A double-site model for drug absorption (Journal of Pharmacokinetics and Biopharmaceutics, 1987)
- Veralipride: Alternative antidopaminergic treatment for menopausal symptoms (American Journal of Obstetrics and Gynecology, 1988)
- Effects of the dopamine antagonist veralipride on hot flushes and luteinizing hormone secretion in postmenopausal women. (Obstetrics & Gynecology, 1988)
- Veralipride versus conjugated oestrogens: A double-blind study in the management of menopausal hot flushes (Current Medical Research and Opinion, 1984)
- Restoration of Luteinizing Hormone Response to Naloxone in Postmenopausal Women by Chronic Administration of the Antidopaminergic Drug Veralipride (The Journal of Clinical Endocrinology and Metabolism, 1988)
- Veralipride for Hot Flushes during Gonadotropin-Releasing Hormone Agonist Treatment (Gynecologic and Obstetric Investigation, 1992)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Agral
- N-(1-allyl-2-pyrrolidinyl)methyl-2,3-dimethoxy-5-sulfamoylbenzamide
- Veraligral
- veralipride monohydrochloride
- Menofel
- Agreal
-
SMILESCOC1=C(C(=CC(=C1)S(=O)(=O)N)C(=O)NCC2CCCN2CC=C)OC
-
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- Pubchem - VERALIPRIDE
- Wikipedia - veralipride
Veralipride (Agreal, Agradil) is a benzamide neuroleptic medicine indicated in the treatment of vasomotor symptoms associated with the menopause. It was first authorised for use in 1979. Veralipride has never gained approval in the United States.
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Synthesis
5-(Aminosulphonyl)-2,3-dimethoxybenzoyl chloride
+
(1-Allylpyrrolidin-2-yl)methanamine
(Schotten-Baumann amide from acid)
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