Weight | 350.462 g/mol |
---|---|
Formula | C22H26N2O2 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
vinpocetine (42971-09-5)
ethyl apovincaminate tartrate (1:1) · TCV-3B · Cavinton
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#889 in Neuroscience
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#3914 in Biology
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#4927 in Chemistry
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- Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability (Journal of Controlled Release, 2006)
- Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle (Biochemical Pharmacology, 1984)
- Preparation and characterization of vinpocetine loaded nanostructured lipid carriers (NLC) for improved oral bioavailability. (International Journal of Pharmaceutics, 2010)
- Vinpocetine inhibits NF-Bdependent inflammation via an IKK-dependent but PDE-independent mechanism (Proceedings of the National Academy of Sciences of the United States of America, 2010)
- Novel sugar esters proniosomes for transdermal delivery of vinpocetine: Preclinical and clinical studies (European Journal of Pharmaceutics and Biopharmaceutics, 2011)
- Role of sodium channel inhibition in neuroprotection: Effect of vinpocetine (Brain Research Bulletin, 2000)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ethyl apovincaminate tartrate (1:1)
- TCV-3B
- Cavinton
- ethyl apovincaminate, 3H-labeled
- ethyl apovincaminate, (16alpha)-isomer
- Kavinton
- ethyl apovincaminate
- ethyl apovincaminate, 2-oxopentanedioate (1:1)
- RGH-4405
- ethyl apovincaminate, (3alpha,16alpha)-isomer
- ethyl apovincaminate, (+-)-isomer
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SMILESCCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC
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InChIKeyDDNCQMVWWZOMLN-UHFFFAOYSA-N
- Pubchem - vinpocetine
- Wikipedia - vinpocetine
Vinpocetine (brand names: Cavinton, Intelectol; chemical name: ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"), an extract from the lesser periwinkle plant. Vinpocetine was first isolated from the plant in 1975 by the Hungarian chemist Csaba Szntay. The mass production of the synthetic compound was started in 1978 by the Hungarian pharmaceutical company Richter Gedeon.
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