| Weight | 429.563 g/mol |
|---|---|
| Formula | C22H23NO4S2 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Zofenopril (81872-10-8)
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- The Effect of the Angiotensin-ConvertingEnzyme Inhibitor Zofenopril on Mortality and Morbidity after Anterior Myocardial Infarction (The New England Journal of Medicine, 1995)
- Cardioprotective effects of zofenopril, a new angiotensin-converting enzyme inhibitor, on doxorubicin-induced cardiotoxicity in the rat. (European Journal of Pharmacology, 2001)
- Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure (British Journal of Pharmacology, 2000)
- Double-blind comparison between zofenopril and lisinopril in patients with acute myocardial infarction: Results of the Survival of Myocardial Infarction Long-term Evaluation-2 (SMILE-2) study (American Heart Journal, 2003)
- Antioxidant and Cardioprotective Properties of the Sulphydryl Angiotensinconverting Enzyme Inhibitor Zofenopril (Journal of International Medical Research, 2005)
- Zofenopril inhibits the expression of adhesion molecules on endothelial cells by reducing reactive oxygen species (American Journal of Hypertension, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)O)SC3=CC=CC=C3
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InChIKeyIAIDUHCBNLFXEF-UHFFFAOYSA-N
- Pubchem - Zofenopril
- Wikipedia - zofenopril
Zofenopril (INN) is a medication that protects the heart and helps reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor. In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs, atenolol and enalapril, and was associated with fewer adverse effects.
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S-Benzoyl-3-mercapto-2-methylpropanoyl chloride
+
L-Proline, 4-(phenylthio)-, trans-
(Schotten-Baumann amide from acid)
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