| Weight | 331.868 g/mol |
|---|---|
| Formula | C18H18ClNOS |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
zotepine (26615-21-4)
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- Improvement of Cognitive Function in Schizophrenic Patients Receiving Clozapine or Zotepine: Results from a Double-Blind Study (Pharmacopsychiatry, 1997)
- A comparison of an atypical and typical antipsychotic, zotepine versus haloperidol in patients with acute exacerbation of schizophrenia: a parallel-group double-blind trial. (Psychopharmacology Bulletin, 1996)
- Zotepine in the treatment of schizophrenic patients with prevailingly negative symptoms. A double-blind trial vs. haloperidol. (International Clinical Psychopharmacology, 1992)
- The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating. (Pharmacology, Biochemistry and Behavior, 2005)
- Zotepine in the Treatment of Negative Symptoms in Chronic Schizophrenia (Pharmacopsychiatry, 1987)
- Zotepine vs. haloperidol in paranoid schizophrenia: a double-blind trial. (Psychopharmacology Bulletin, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H361: Suspected of damaging fertility or the unborn child
Warning Reproductive toxicity - Category 2 - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 -
SMILESCN(C)CCOC1=CC2=CC=CC=C2SC3=C1C=C(C=C3)Cl
-
InChIKeyHDOZVRUNCMBHFH-UHFFFAOYSA-N
- Pubchem - zotepine
- Wikipedia - zotepine
Zotepine (brand names: Losizopilon (JP), Lodopin (ID, JP), Setous (JP), Zoleptil (CZ, PT, TR, UK); where indicates a formulation that has been discontinued) is an atypical antipsychotic drug indicated for acute and chronic schizophrenia. It has been used in Germany since 1990 (although it has been discontinued in Germany) and Japan since 1982. Zotepine is not approved for use in the United States, United Kingdom, Australia, Canada or New Zealand.
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zotepine
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