| Weight | 179.238 g/mol |
|---|---|
| Formula | C11H14FN |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
2-(4-fluorophenyl)piperidine (383128-03-8)
383128-03-8
Suppliers
Most-cited Publications
- DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles. (Journal of Pharmacology and Experimental Therapeutics, 1992)
- Structure-activity relationship studies of novel 4-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs : synthesis and biological evaluation at the dopamine and serotonin transporter sites (Journal of Medicinal Chemistry, 1996)
- Autoradiographic identification and characterization of receptors in guinea pig brain using [3H]1(cyclopropylmethyl)-4-(2-(4-fluorophenyl)-2-oxoethyl) piperidine ([3H]DuP 734), a novel receptor ligand (Brain Research, 1992)
- DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects. (Journal of Pharmacology and Experimental Therapeutics, 1992)
- Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (gbr 12909): High affinity ligands for the dopamine transporter (Journal of Medicinal Chemistry, 2002)
- Structureactivity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter (Bioorganic & Medicinal Chemistry, 2006)
Alternate Names
- 383128-03-8
-
SMILESC1CCNC(C1)C2=CC=C(C=C2)F
-
InChIKeyIAQQDIGGISSSQO-UHFFFAOYSA-N
Estimated Properties
| Boiling Point | 254.16 C | EPA T.E.S.T. |
|---|---|---|
| Boiling Point | 261.94 C | EPI Suite |
| Density | 1.1 g/cm3 | EPA T.E.S.T. |
| Flash Point | 127.13 C | EPA T.E.S.T. |
| Melting Point | 57.03 C | EPI Suite |
| Water Solubility | 297.17 mg/L | EPA T.E.S.T. |
| Water Solubility | 3206.2 mg/L | EPI Suite |
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2-(4-fluorophenyl)piperidine
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