| Weight | 162.148 g/mol |
|---|---|
| Formula | C8H6N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
1H-Benzimidazole-2-carboxylic acid (2849-93-6)
2849-93-6
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- Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116). (Journal of Pharmacology and Experimental Therapeutics, 1993)
- Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists (Journal of Medicinal Chemistry, 1990)
- Lanthanide coordination compounds with 1H-benzimidazole-2-carboxylic acid: syntheses, structures and spectroscopic properties (CrystEngComm, 2013)
- THE CRYSTAL AND MOLECULAR STRUCTURE OF TWO BENZIMIDAZOLE DERIVATIVES : 1-(PHENYLMETHYL)-2-(4-METHOXYPHENYLMETHYL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID ( I) AND 1,2-DI-(PHENYLMETHYL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID (II) (Journal of Molecular Structure, 1998)
- A Novel and Orally Active Poly(ADP-Ribose) Polymerase Inhibitor, KR-33889 [2-[Methoxycarbonyl(4-methoxyphenyl) methylsulfanyl]-1H-benzimidazole-4-carboxylic Acid Amide], Attenuates Injury in in Vitro Model of Cell Death and in Vivo Model of Cardiac Ischemia (Journal of Pharmacology and Experimental Therapeutics, 2009)
- The angiotensin receptor antagonist 2-ethoxy-1-[[2'-(1H- tetrazol-5-yl) biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV11974) attenuates the tubuloglomerular feedback response during NO synthase blockade in rats. (Journal of Pharmacology and Experimental Therapeutics, 1996)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2849-93-6
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SMILESC1=CC=C2C(=C1)NC(=N2)C(=O)O
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InChIKeyRHXSYTACTOMVLJ-UHFFFAOYSA-N
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