Weight | 163.102 g/mol |
---|---|
Formula | C5H4F3N3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
2-Amino-4-(trifluoromethyl)pyrimidine (16075-42-6)
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- QSAR study of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl) pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kappa B mediated gene expression based on support vector machines. (Journal of Chemical Information and Computer Sciences, 2003)
- StructureActivity Relationship Studies of Ethyl 2[(3Methyl2,5dioxo(3pyrrolinyl))amino] 4(trifluoromethyl)pyrimidine5carboxylate: An Inhibitor of AP1 and NFB Mediated Gene Expression. (Bioorganic & Medicinal Chemistry Letters, 2002)
- Novel inhibitors of AP-1 and NF-B mediated gene expression: structureactivity relationship studies of ethyl 4-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate (Bioorganic & Medicinal Chemistry Letters, 2000)
- Reactions with 3-Amino-5-trifluoromethyl-1,2,4-triazole: a Simple Route to Fluorinated Poly-substituted Triazolo[1,5-a]pyrimidine and Triazolo[5,1-c]triazine Derivatives (Journal of Chemical Research-s, 1997)
- Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia (Journal of Medicinal Chemistry, 2016)
- 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln 4-amino-2- (imidazolidin-2-on-1-yl) -pyrimidine-5-carboxylic acid (N- (3-trifluoromethyl-phenyl) -amides) for antithrombotic prophylaxis and treatment as well as their use for the preparation of antithrombotically active medicinal products (1985)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CN=C(N=C1C(F)(F)F)N
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InChIKeyNKOTXYPTXKUCDL-UHFFFAOYSA-N
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