Weight | 100.146 g/mol |
---|---|
Formula | C3H4N2S |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
2-AMINOTHIAZOLE (96-50-4)
T157602 · 2-aminothiazole sulfate (1:1) · 2-aminothiazole mononitrate
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- 2-Aminothiazole as a Novel Kinase Inhibitor Template. StructureActivity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase Inhibitor (Journal of Medicinal Chemistry, 2006)
- N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent. (Journal of Medicinal Chemistry, 2004)
- Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-Ray Crystallographic Analysis, and Biological Activities (Journal of Medicinal Chemistry, 2002)
- Dopamine autoreceptor agonists: resolution and pharmacological activity of 2,6-diaminotetrahydrobenzothiazole and an aminothiazole analogue of apomorphine (Journal of Medicinal Chemistry, 1987)
- A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries (Bioorganic & Medicinal Chemistry Letters, 1996)
- Copper determination in ethanol fuel by differential pulse anodic stripping voltammetry at a solid paraffin-based carbon paste electrode modified with 2-aminothiazole organofunctionalized silica. (Talanta, 2007)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - T157602
- 2-aminothiazole sulfate (1:1)
- 2-aminothiazole mononitrate
-
SMILESC1=CSC(=N1)N
-
InChIKeyRAIPHJJURHTUIC-UHFFFAOYSA-N
- Pubchem - 2-AMINOTHIAZOLE
- Wikipedia - aminothiazole
2-Aminothiazole is a heterocyclic amine featuring an thiazole core. It can also be considered a cyclic isothiourea. It possesses an odor similar to pyridine and is soluble in water, alcohols and diethyl ether.
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