Weight | 128.156 g/mol |
---|---|
Formula | C4H4N2OS |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
2-thiouracil (141-90-2)
Thiouracil
Score:
#2526 in Biology
,
#3148 in Chemistry
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- TREATMENT OF HYPERTHYROIDISM WITH THIOUREA AND THIOURACIL (JAMA, 1943)
- Myocardial Infarction in Rats Fed Diets Containing High Fat, Cholesterol, Thiouracil, and Sodium Cholate (Circulation, 1959)
- Thiobases in Escherchia coli Transfer RNA: 2-Thiocytosine and 5-Methylaminomethyl-2-thiouracil (Science, 1968)
- The effect of thyroid deficiency induced by methyl thiouracil on the maturation of the central nervous system. (Journal of Anatomy, 1951)
- Atherosclerosis and arteriosclerosis in dogs following ingestion of cholesterol and thiouracil. (Archives of pathology, 1946)
- Upregulation of the angiogenic factors PlGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization. (Oncogene, 1997)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H303: May be harmful if swallowed
Warning Acute toxicity, oral - Category 5 - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - H411: Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard - Category 2 - Thiouracil
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SMILESC1=CNC(=S)NC1=O
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InChIKeyZEMGGZBWXRYJHK-UHFFFAOYSA-N
- Pubchem - 2-thiouracil
- Wikipedia - thiouracil
Thiouracil refers both to a specific molecule consisting of a sulfated uracil, and a family of molecules based upon that structure.
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