| Weight | 189.136 g/mol |
|---|---|
| Formula | C8H6F3NO |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
2-(Trifluoromethyl)benzamide (360-64-5)
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- Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant. (Journal of Medicinal Chemistry, 2010)
- Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro. (Biochemical Pharmacology, 2010)
- Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activated Receptor (PPAR) Antagonist (Journal of Medicinal Chemistry, 2010)
- Synthesis and preliminary in vivo evaluation of 4[123I]iodoN{2[4(6trifluoromethyl2pyridinyl)1piperazinyl]ethyl}benzamide, a potential SPECT radioligand for the 5HT1A receptor (Journal of Labelled Compounds and Radiopharmaceuticals, 2001)
- 2-Chloro-N-[(S)-phenyl [(2S)-piperidin-2-yl] methyl]-3-trifluoromethyl benzamide, monohydrochloride, an inhibitor of the glycine transporter type 1, increases evoked-dopamine release in the rat nucleus accumbens in vivo via an enhanced glutamatergic neurotransmission. (Neuroscience, 2006)
- IN VITRO METABOLISM OF MK-0767 [()-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)-PHENYL] METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR / AGONIST. II. IDENTIFICATION OF METABOLITES BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY (Drug Metabolism and Disposition, 2004)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1=CC=C(C(=C1)C(=O)N)C(F)(F)F
-
InChIKeyQBAYIBZITZBSFO-UHFFFAOYSA-N
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