| Weight | 271.196 g/mol |
|---|---|
| Formula | C8H20Cl2N6 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
2997-92-4 (2997-92-4)
ABAP · AAPH · AMPH cpd
Score:
#2184 in Biochemistry
,
#4450 in Biology
,
#5630 in Chemistry
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- DNA BREAKING ACTIVITY OF THE CARBON-CENTERED RADICAL GENERATED FROM 2,2 '-AZOBIS(2-AMIDINOPROPANE) HYDROCHLORIDE (AAPH) (Free Radical Research, 1993)
- Antioxidant activity of phenolic compounds in 2,2-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced oxidation: Synergistic and antagonistic effects (Journal of the American Oil Chemists' Society, 2003)
- Concentration dependent antioxidant/pro-oxidant activity of curcumin Studies from AAPH induced hemolysis of RBCs (Chemico-Biological Interactions, 2008)
- Oxidative insult to human red blood cells induced by free radical initiator AAPH and its inhibition by a commercial antioxidant mixture (Life Sciences, 2001)
- In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe2+/H2O2: Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders (Neurochemistry International, 2006)
- Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH (Journal of Lipid Research, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - ABAP
- AAPH
- AMPH cpd
- 2,2'-azobis(2-amidinopropane) acetate
- 2,2'-azobis(2-amidinopropane)
- 2,2'-azobis(2-amidinopropane) dihydrochloride
- ABAPH
- 2,2'-azobis(2-amidinopropane) monohydrochloride
- 2,2'-azo-bis(2-amidinopropane)
- 2,2'-azobis(2-methylpropaneimidamide) dihydrochloride
- 2,2'-azobis(2-amidinopropane)dihydrochloride
- 2,2'-azobis(2-methylpropionamidine)
-
SMILESCC(C)(C(=N)N)N=NC(C)(C)C(=N)N.Cl.Cl
-
InChIKeyLXEKPEMOWBOYRF-UHFFFAOYSA-N
- Pubchem - 2997-92-4
- Wikipedia - 2,2'-Azobis(2-amidinopropane) dihydrochloride
2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) is a chemical compound used to study the chemistry of the oxidation of drugs. It is a free radical-generating azo compound. It is gaining prominence as a model oxidant in small molecule and protein therapeutics for its ability to initiate oxidation reactions via both nucleophilic and free radical mechanisms.
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