| Weight | 136.076 g/mol |
|---|---|
| Formula | C4H3F3N2 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
4-(trifluoromethyl)-1H-pyrazole (52222-73-8)
52222-73-8
"What do you need help with?"
LabBot
- Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. (Journal of Medicinal Chemistry, 2001)
- Discovery of 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride (Razaxaban), a Highly Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor (Journal of Medicinal Chemistry, 2005)
- Disposition of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]- 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC 423) by novel metabolic pathways. Characterization of unusual metabolites by liquid chromatography/mass spectrometry and NMR (Chemical Research in Toxicology, 2002)
- Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice. (Life Sciences, 2008)
- Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies. (Bioorganic & Medicinal Chemistry, 2008)
- A TRPC3 Blocker, Ethyl-1-(4-(2,3,3-Trichloroacrylamide)Phenyl)-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxylate (Pyr3), Prevents Stent-Induced Arterial Remodeling (Journal of Pharmacology and Experimental Therapeutics, 2013)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 52222-73-8
-
SMILESC1=C(C=NN1)C(F)(F)F
-
InChIKeyKDEJQUNODYXYBJ-UHFFFAOYSA-N
Suppliers
Most-cited Publications
Safety
Alternate Names
Estimated Properties
| Boiling Point | 208 C | EPA T.E.S.T. |
|---|---|---|
| Boiling Point | 181.8 C | EPI Suite |
| Density | 1.41 g/cm3 | EPA T.E.S.T. |
| Flash Point | 110.21 C | EPA T.E.S.T. |
| Melting Point | 15.5 C | EPI Suite |
| Water Solubility | 45905.2 mg/L | EPA T.E.S.T. |
| Water Solubility | 4996.6 mg/L | EPI Suite |
External Links
Similar Compounds
4-Cyanopyrazole
(31108-57-3)
2 alternate names
3 suppliers
(1H-PYRAZOL-4-YL)METHANOL
(25222-43-9)
2 alternate names
3 suppliers
4-ethyl-1H-pyrazole
(17072-38-7)
2 alternate names
3 suppliers
4-Propyl-1H-pyrazole
(21037-81-0)
2 alternate names
3 suppliers
4-(propan-2-yl)-1H-pyrazole hydrochloride
(1390654-61-1)
2 alternate names
3 suppliers
4-(2-Chloroethyl)-1H-pyrazole hydrochloride
(103433-17-6)
2 alternate names
3 suppliers
2-(1H-pyrazol-4-yl)ethanol
(180207-57-2)
2 alternate names
3 suppliers
2-(1H-pyrazol-4-yl)ethanamine
(6429-11-4)
2 alternate names
3 suppliers
1,4-Dimethylpyrazole
(1072-68-0)
2 alternate names
3 suppliers
1H-Pyrazole-4-carboxylic acid
(37718-11-9)
2 alternate names
3 suppliers
3-(1H-pyrazol-4-yl)propan-1-ol
(60951-21-5)
2 alternate names
3 suppliers
21056-78-0
(21056-78-0)
2 alternate names
3 suppliers
N-methyl-2-(1H-pyrazol-4-yl)ethanamine
(956949-79-4)
2 alternate names
3 suppliers
N-methyl-2-(1H-pyrazol-4-yl)ethanamine dihydrochloride
(1609403-02-2)
2 alternate names
3 suppliers
3,4,5-Trimethyl-1H-pyrazole
(5519-42-6)
2 alternate names
3 suppliers
3-(Trifluoromethyl)pyridine
(3796-23-4)
2 alternate names
3 suppliers
4-(chloromethyl)-1-methyl-1H-pyrazole
(735241-98-2)
2 alternate names
3 suppliers
4-(1H-Pyrazol-4-yl)butanoic acid
(84302-87-4)
2 alternate names
3 suppliers
1H-pyrazole-4-carbohydrazide
(87551-45-9)
2 alternate names
3 suppliers
(1-methyl-1H-pyrazol-4-yl)methanol
(112029-98-8)
2 alternate names
3 suppliers
3-(1H-Pyrazol-4-yl)propanoic acid
(1174309-53-5)
2 alternate names
3 suppliers
1-Methyl-1H-pyrazole-4-carbaldehyde
(25016-11-9)
2 alternate names
3 suppliers
(1-methyl-1H-pyrazol-4-yl)methanamine
(400877-05-6)
2 alternate names
3 suppliers
4-Methylpyridazine
(1120-88-3)
2 alternate names
3 suppliers
4-(2-bromoethyl)-1-methyl-1H-pyrazole
(1240960-12-6)
2 alternate names
3 suppliers
(3,5-dimethyl-1H-pyrazol-4-yl)methanol
(89600-69-1)
2 alternate names
3 suppliers
2-(4-METHYL-1H-PYRAZOL-1-YL)ETHANOL HYDROCHLORIDE
(1609395-63-2)
2 alternate names
3 suppliers
3-(difluoromethyl)pyridine
(76541-44-1)
2 alternate names
3 suppliers
Ethyl 4-pyrazolecarboxylate
(37622-90-5)
2 alternate names
3 suppliers
(3,5-Dimethyl-1H-pyrazol-4-yl)methanamine
(518064-16-9)
2 alternate names
3 suppliers
N-methyl-1-(1-methyl-1H-pyrazol-4-yl)methanamine
(179873-43-9)
2 alternate names
3 suppliers
16617-46-2
(16617-46-2)
2 alternate names
3 suppliers
3,5-Bis(trifluoromethyl)-1H-pyrazole
(14704-41-7)
2 alternate names
3 suppliers
2-(1-methyl-1H-pyrazol-4-yl)ethanol
(176661-75-9)
2 alternate names
3 suppliers
2-(1-methyl-1H-pyrazol-4-yl)ethanamine
(796845-58-4)
2 alternate names
3 suppliers
2-(1-Methyl-1H-pyrazol-4-yl)ethan-1-amine dihydrochloride
(1431962-30-9)
2 alternate names
3 suppliers
4-Chloropyrazole
(15878-00-9)
2 alternate names
3 suppliers
4-Ethyl-3,5-dimethyl-1H-pyrazole
(7554-67-8)
2 alternate names
3 suppliers
[2-(4-methyl-1H-pyrazol-1-yl)ethyl]amine dihydrochloride
(1609396-60-2)
2 alternate names
3 suppliers
(1-ethyl-1H-pyrazol-4-yl)methanol
(905307-04-2)
2 alternate names
3 suppliers
3,5-Dimethylpyrazole
(67-51-6)
2 alternate names
3 suppliers
3-Methylpyrazole
(88054-14-2, 1453-58-3)
2 alternate names
3 suppliers
1-Ethyl-1H-pyrazole-4-carbaldehyde
(304903-10-4)
2 alternate names
3 suppliers
4-(Chloromethyl)-1-ethyl-1H-pyrazole hydrochloride
(1332529-52-8)
2 alternate names
3 suppliers
1-(1-ethyl-1H-pyrazol-4-yl)methanamine
(856696-09-8)
2 alternate names
3 suppliers
3,5-dimethyl-1H-pyrazole-4-carbaldehyde
(201008-71-1)
2 alternate names
3 suppliers
4-(Trifluoromethyl)pyridine
(3796-24-5)
2 alternate names
3 suppliers
1-methyl-1H-pyrazole-4-carboxylic acid
(5952-92-1)
2 alternate names
3 suppliers
MolPort-029-997-912
2 alternate names
3 suppliers
3-(1-methyl-1H-pyrazol-4-yl)propan-1-ol
(192661-38-4)
2 alternate names
3 suppliers
4-fluoro-1H-pyrazole
(35277-02-2)
2 alternate names
3 suppliers
1-(1-methyl-1H-pyrazol-4-yl)ethanone
(37687-18-6)
2 alternate names
3 suppliers
N-[(1-methyl-1H-pyrazol-4-yl)methyl]ethanamine
(949095-17-4)
2 alternate names
3 suppliers
1H-pyrazol-4-ol hydrochloride
(1803591-08-3)
2 alternate names
3 suppliers
1H-Pyrazol-4-ol
(4843-98-5)
2 alternate names
3 suppliers
3-(4-methyl-1H-pyrazol-1-yl)propan-1-amine
(956758-69-3)
2 alternate names
3 suppliers
5-(trifluoromethyl)pyridin-2-amine
(74784-70-6)
2 alternate names
3 suppliers
N-Methyl-2-(1-methyl-1H-pyrazol-4-yl)ethanamine
(1093879-63-0)
2 alternate names
3 suppliers
33252-63-0
(33252-63-0)
2 alternate names
3 suppliers
BENZOTRIFLUORIDE
(98-08-8)
2 alternate names
2 safety hazards
3 suppliers
3-(1-methyl-1H-pyrazol-4-yl)propan-1-amine
(1211488-02-6)
2 alternate names
3 suppliers
[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]amine dimethanesulfonate
(1559059-71-0)
2 alternate names
3 suppliers
3-(difluoromethyl)-5-methyl-1H-pyrazole
(934759-09-8)
2 alternate names
3 suppliers
4-(2-Bromoethyl)-3,5-dimethyl-1H-pyrazole
(83467-28-1)
2 alternate names
3 suppliers
(4-methyl-1H-pyrazol-1-yl)acetic acid hydrate
(1609396-02-2)
2 alternate names
3 suppliers
N-methyl-2-(4-methyl-1H-pyrazol-1-yl)ethanamine hydrochloride hydrate
(1177297-64-1)
2 alternate names
3 suppliers
3,5-bis(difluoromethyl)-1H-pyrazole
(77614-79-0)
2 alternate names
3 suppliers
1H-pyrazol-4-amine hydrochloride
(4331-28-6)
2 alternate names
3 suppliers
1H-Pyrazol-4-amine
(28466-26-4)
2 alternate names
3 suppliers
N-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1-propanamine
(1227465-68-0)
2 alternate names
3 suppliers
Pyridine, 4-(trifluoromethyl)-, 1-oxide
(22253-59-4)
2 alternate names
3 suppliers
2-methyl-N-[(1-methyl-1H-pyrazol-4-yl)methyl]propan-1-amine
(1015845-80-3)
2 alternate names
3 suppliers
2-Chloro-5-(trifluoromethyl)pyridine
(52334-81-3)
2 alternate names
3 suppliers
1-(3-chloropropyl)-4-methyl-1H-pyrazole hydrochloride
(1609396-41-9)
2 alternate names
3 suppliers
7-(trifluoromethyl)-1H-indazol-3-amine
(60330-35-0)
2 alternate names
3 suppliers
1-(2-chloroethyl)-1H-pyrazole-4-carbaldehyde
(864723-36-4)
2 alternate names
3 suppliers
1-methyl-1H-pyrazole-4-carbohydrazide
(170020-91-4)
2 alternate names
3 suppliers
N-[(1-methyl-1H-pyrazol-4-yl)methyl]propan-2-amine
(1015846-23-7)
2 alternate names
3 suppliers
2-{[(1-METHYL-1H-PYRAZOL-4-YL)METHYL]-AMINO}ETHANOL DIHYDROCHLORIDE
(1185302-33-3)
2 alternate names
3 suppliers
2-(3,5-dimethyl-1H-pyrazol-4-yl)ethanol
(83467-31-6)
2 alternate names
3 suppliers
2-(3,5-dimethyl-1H-pyrazol-4-yl)ethanamine
(423176-38-9)
2 alternate names
3 suppliers
MolPort-029-906-622
2 alternate names
3 suppliers
AC1LC0Z4
(689251-97-6)
2 alternate names
3 suppliers
689251-97-6
(689251-97-6)
2 alternate names
3 suppliers
1-(1-ethyl-1H-pyrazol-4-yl)-N-methylmethanamine
(1002651-68-4)
2 alternate names
3 suppliers
pyridazine-4-carbaldehyde
(50901-42-3)
2 alternate names
3 suppliers
3,5-dimethyl-4-propyl-1H-pyrazole
(81328-51-0)
2 alternate names
3 suppliers
4-(2-chloroethyl)-3,5-dimethyl-1H-pyrazole
(79379-05-8)
2 alternate names
3 suppliers
1,4-Bis(trifluoromethyl)benzene
(433-19-2)
2 alternate names
3 suppliers
4-Methylbenzotrifluoride
(6140-17-6)
2 alternate names
3 suppliers
(1-Isopropyl-1H-pyrazol-4-yl)methanol
(1007542-22-4)
2 alternate names
3 suppliers
1H-Pyrazol-3-ol
(52277-85-7)
2 alternate names
3 suppliers
3-(1-methyl-1H-pyrazol-4-yl)propanoic acid
(796845-56-2)
2 alternate names
3 suppliers
2-Chloro-3-(trifluoromethyl)pyridine
(65753-47-1)
2 alternate names
4 safety hazards
3 suppliers
1-VINYL-1H-PYRAZOLE-4-CARBALDEHYDE
(864723-38-6)
2 alternate names
3 suppliers
[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]amine diethanedioate hydrate
2 alternate names
3 suppliers
4-(trifluoromethyl)-1H-pyrazole
CAS Directory
