Weight | 153.137 g/mol |
---|---|
Formula | C7H7NO3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
5-Aminosalicylic acid (89-57-6)
Mesalamine · Asacol · Pentasa
Score:
#128 in Biochemistry
,
#566 in Biology
,
#602 in Chemistry
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- Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. (The New England Journal of Medicine, 1987)
- Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial. (BMJ, 1989)
- 5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. (Gastroenterology, 1987)
- Solubilities ofo-acetylsalicylic, 4-aminosalicylic, 3,5-dinitrosalicylic, andp-toluic acid, and magnesium-DL-aspartate in water fromT=(278 to 348) K (The Journal of Chemical Thermodynamics, 1999)
- Mesalamine in the maintenance treatment of Crohn's disease: A meta-analysis adjusted for confounding variables (Gastroenterology, 1997)
- Postoperative maintenance of Crohns disease remission with 6-mercaptopurine, mesalamine, or placebo: A 2-year trial (Gastroenterology, 2004)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mesalamine
- Asacol
- Pentasa
- Mesalazine
- Rowasa
- Salofalk
- Canasa
- Mesasal
- Claversal
- 5 Aminosalicylic Acid
- Mesalamine Monosodium Salt
- 5-Aminosalicylate
- m-Aminosalicylic Acid
- Novo 5 ASA
- m Aminosalicylic Acid
- meta-Aminosalicylic Acid
- Novo-5 ASA
- Ascolitin
- 5 Aminosalicylate
- Novo5 ASA
- Lixacol
- Mesalamine Hydrochloride
- Fivasa
- meta Aminosalicylic Acid
- Asacolon
-
SMILESC1=CC(=C(C=C1N)C(=O)O)O
-
InChIKeyKBOPZPXVLCULAV-UHFFFAOYSA-N
- Pubchem - 5-Aminosalicylic acid
- Wikipedia - mesalamine
Mesalazine (INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn's disease. It is sold in an oral form to maintain remission in Crohn's disease, and as a rectal suppository and an enema for the lower bowel conditions. It is generic and sold under many brand names worldwide, and there are many formulations.
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Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
Estimated Properties
Boiling Point | 316.38 C | EPA T.E.S.T. |
---|---|---|
Density | 1.49 g/cm3 | EPA T.E.S.T. |
Flash Point | 194.96 C | EPA T.E.S.T. |
Water Solubility | 3793.16 mg/L | EPA T.E.S.T. |
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Similar Compounds
Sodium 5-amino-2-hydroxybenzoate
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methyl 5-amino-2-methoxybenzoate
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methyl 5-acetamido-2-hydroxybenzoate
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methyl 2-hydroxy-5-nitrobenzoate
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3-Aminobenzoic acid hydrochloride
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2,6-dihydroxy-4-methylbenzoic acid
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Pas ethyl ester
(6059-17-2)
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(2840-26-8, 2840-76-8)
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5-Methoxysalicylic acid
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(4365-31-5)
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methyl 3-amino-5-chloro-2-hydroxybenzoate
(5043-81-2)
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333395-43-0
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