| Weight | 241.294 g/mol |
|---|---|
| Formula | C14H15N3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
Ampalex (154235-83-3)
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SMILESC1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
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- Wikipedia - cx516
CX-516 is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator and is being developed by a collaboration of Cortex and Shire and Servier. It was researched as a treatment for Alzheimer's disease under the brand name Ampalex, and was also being examined as a treatment for ADHD. CX-516 was the first ampakine compound developed by Cortex and while it showed good in vitro activity and positive results in animal tests, the human trials proved disappointing due mainly to low potency and short half-life.
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