| Weight | 394.73 g/mol |
|---|---|
| Formula | C16H22Cl3N3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
Bendamustine hydrochloride (3543-75-7)
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- Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines. (Anti-Cancer Drugs, 1996)
- Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride (Cancer Chemotherapy and Pharmacology, 2007)
- Bendamustine prolongs progression-free survival in metastatic breast cancer (MBC): a phase III prospective, randomized, multicenter trial of bendamustine hydrochloride, methotrexate and 5-fluorouracil (BMF) versus cyclophosphamide, methotrexate and 5-fluorouracil (CMF) as first-line treatment of MBC. (Anti-Cancer Drugs, 2005)
- A phase I study of bendamustine hydrochloride administered day 1+2 every 3 weeks in patients with solid tumours (British Journal of Cancer, 2007)
- Bendamustine hydrochloride in patients with refractory soft tissue sarcoma: a noncomparative multicenter phase 2 study of the German sarcoma group (AIO-001). (Cancer, 2007)
- Phase I and pharmacokinetic study of bendamustine hydrochloride in relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma (Cancer Science, 2010)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
-
InChIKeyZHSKUOZOLHMKEA-UHFFFAOYSA-N
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