| Weight | 424.088 g/mol |
|---|---|
| Formula | C17H12Br2O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
benzbromarone (3562-84-3)
Acifugan · Benzbromaron AL · Besuric
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- Sigma-Aldrich - benzbromarone50.10 - 168.00 USD
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- Efficacy of allopurinol and benzbromarone for the control of hyperuricaemia. A pathogenic approach to the treatment of primary chronic gout (Annals of the Rheumatic Diseases, 1998)
- A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients? (Drug Safety, 2008)
- A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300600 mg/day versus benzbromarone 100200 mg/day in patients with gout (Annals of the Rheumatic Diseases, 2009)
- Mechanisms of benzarone and benzbromaroneinduced hepatic toxicity (Hepatology, 2005)
- Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol (Annals of the Rheumatic Diseases, 2008)
- Uric Acid-Lowering Treatment With Benzbromarone in Patients With Heart Failure A Double-Blind Placebo-Controlled Crossover Preliminary Study (Circulation-heart Failure, 2010)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Acifugan
- Benzbromaron AL
- Besuric
- Heumann Brand of Benzbromarone
- Desuric
- Benzbromarone Aliud Brand
- Benzbromarone Heumann Brand
- Sanofi Winthrop Brand of Benzbromarone
- Aliud Brand of Benzbromarone
- ratiopharm Brand of Benzbromarone
- Benzbromaron ratiopharm
- Benzbromaron-ratiopharm
- Benzbromarone Sanfer Brand
- Narcaricin
- Benzbromaron
- Benzbromarone ratiopharm Brand
- Urinorm
- Benzbromaronratiopharm
- Sanfer Brand of Benzbromarone
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SMILESCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br
-
InChIKeyWHQCHUCQKNIQEC-UHFFFAOYSA-N
- Pubchem - benzbromarone
- Wikipedia - benzbromarone
Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone. Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a non-uricosuric xanthine oxidase inhibitor, and probenecid, another uricosuric drug.
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benzbromarone
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