| Weight | 383.831 g/mol |
|---|---|
| Formula | C21H18ClNO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 2 |
Chelerythrine chloride (3895-92-9)
chelerythrine · chelerythrine hydroxide · chelerythrine sulfate
Score:
#2252 in Physics
,
#2843 in Biochemistry
,
#6968 in Chemistry
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- Chelerythrine is a potent and specific inhibitor of protein kinase C (Biochemical and Biophysical Research Communications, 1990)
- Identification of chelerythrine as an inhibitor of BclXL function. (Journal of Biological Chemistry, 2003)
- In Vitro and in Vivo Activity of Protein Kinase C Inhibitor Chelerythrine Chloride Induces Tumor Cell Toxicity and Growth Delay in Vivo (Clinical Cancer Research, 2000)
- Chelerythrine Rapidly Induces Apoptosis through Generation of Reactive Oxygen Species in Cardiac Myocytes (Journal of Molecular and Cellular Cardiology, 2001)
- Activation of p38 and c-Jun N-terminal Kinase Pathways and Induction of Apoptosis by Chelerythrine Do Not Require Inhibition of Protein Kinase C (Journal of Biological Chemistry, 2000)
- Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment (Food and Chemical Toxicology, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - chelerythrine
- chelerythrine hydroxide
- chelerythrine sulfate
- norchelerythrine
-
SMILESC[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-]
-
InChIKeyWEEFNMFMNMASJY-UHFFFAOYSA-M
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Chelerythrine chloride
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