| Weight | 268.187 g/mol |
|---|---|
| Formula | C14H15Cl2N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Chlornaphazine (494-03-1)
chlornaphazin
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- Bladder tumours induced by chlornaphazine. A five-year follow-up study of chlornaphazine-treated patients with polycythaemia. (Acta Medica Scandinavica, 2009)
- CHLORNAPHAZINE AS A BLADDER CARCINOGEN. (Acta Medica Scandinavica, 2009)
- Mutagenicity to bacteria, cultured cells, and rodents of the human carcinogen chlornaphazine (Environmental Mutagenesis, 1988)
- Cancer of the bladder in patients treated with chlornaphazine. (BMJ, 1970)
- Chlornaphazine and chlorambucil induce dominant lethal mutations in male mice (Mutation Research-reviews in Mutation Research, 2003)
- BLADDER CANCER DEVELOPING DURING TREATMENT WITH CHLORNAPHAZIN (ERYSAN) (Ugeskrift for Lger, 1964)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - chlornaphazin
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SMILESC1=CC=C2C=C(C=CC2=C1)N(CCCl)CCCl
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InChIKeyXCDXSSFOJZZGQC-UHFFFAOYSA-N
- Pubchem - Chlornaphazine
- Wikipedia - chlornaphazine
Chlornaphazine, a derivative of 2-naphthylamine, is a nitrogen mustard that was developed in the 1950s for the treatment of polycythemia and Hodgkin's disease. However, a high incidence of bladder cancers in patients receiving treatment with chlornaphthazine led to use of the drug being discontinued. The International Agency for Research on Cancer has listed chlornaphazine as a human carcinogen.
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