| Weight | 360.915 g/mol |
|---|---|
| Formula | CH10Cl2Na2O10P2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
CLODRONATE DISODIUM (88416-50-6, 22560-50-5)
Clodronate · Dichloromethylene Diphosphonate · Dichloromethane Diphosphonate
Score:
#2347 in Biochemistry
,
#4655 in Biology
,
#5908 in Chemistry
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- Reduction in new metastases in breast cancer with adjuvant clodronate treatment (The New England Journal of Medicine, 1998)
- Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer. (Journal of Clinical Oncology, 1993)
- Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl 2 MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats. (Calcified Tissue International, 1973)
- Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach (British Journal of Cancer, 2006)
- Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(,-dichloromethylene) triphosphate, by mammalian cells in vitro (Journal of Bone and Mineral Research, 1997)
- Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer. (Journal of Clinical Oncology, 2002)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Clodronate
- Dichloromethylene Diphosphonate
- Dichloromethane Diphosphonate
- Dichloromethanediphosphonic Acid
- Cl2MDP
- Dichloromethylene Biphosphonate
- Dichloromethylenebisphosphonate
- Bonefos
- Clodronic Acid
- Clodronate Sodium
- Dichloromethanediphosphonate
-
SMILESC(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.O.O.O.O.[Na+].[Na+]
-
InChIKeyXWHPUCFOTRBMGS-UHFFFAOYSA-L
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