| Weight | 240.214 g/mol |
|---|---|
| Formula | C14H8O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
danthron (117-10-2)
chrysazin · Danthane · Dorbanex
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- Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. (Chemical Research in Toxicology, 2011)
- Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated? (Mutation Research\/genetic Toxicology, 1996)
- Induction of intestinal tumours in rats by chrysazin. (British Journal of Cancer, 1985)
- Carcinogenicity of chrysazin in large intestine and liver of mice (Japanese Journal of Cancer Research, 1986)
- Ultrafast excited-state proton transfer dynamics of 1,8-dihydroxyanthraquinone (chrysazin) studied by femtosecond time-resolved fluorescence spectroscopy (Chemical Physics Letters, 2000)
- Inhibition of DNA replication and repair by anthralin or danthron in cultured human cells (Journal of Investigative Dermatology, 1982)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 - chrysazin
- Danthane
- Dorbanex
- Duolax
- danthrone
- 1,8-dihydroxyanthraquinone
-
SMILESC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
-
InChIKeyQBPFLULOKWLNNW-UHFFFAOYSA-N
- Pubchem - danthron
- Wikipedia - danthron
Dantron (INN), also known as chrysazin or 1,8-dihydroxyanthraquinone, is an organic substance, formally derived from anthraquinone by the replacement of two hydrogen atoms by hydroxyl groups (OH). It is used in some countries as a stimulant laxative. It should not be confused with ondansetron, an unrelated drug that was marketed in South Africa under the trade name "Dantron".
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danthron
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