| Weight | 248.307 g/mol |
|---|---|
| Formula | C12H12N2O2S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Dapsone (80-08-0)
Diaminodiphenylsulfone · DADPS · Sulfona
Score:
#18 in Microbiology
,
#93 in Neuroscience
,
#490 in Biology
,
#514 in Chemistry
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- Molecular Markers for Failure of Sulfadoxine-Pyrimethamine and Chlorproguanil-Dapsone Treatment of Plasmodium falciparum Malaria (The Journal of Infectious Diseases, 2002)
- Dapsone and sulfones in dermatology: Overview and update (Journal of The American Academy of Dermatology, 2001)
- Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy. (Annals of Internal Medicine, 1982)
- Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania. (The Lancet, 2001)
- Clinical Pharmacokinetics of Dapsone (Clinical Pharmacokinectics, 1986)
- Treatment of cicatricial (benign mucous membrane) pemphigoid with dapsone (Journal of The American Academy of Dermatology, 1982)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - Diaminodiphenylsulfone
- DADPS
- Sulfona
- Sulfonyldianiline
- Dapson-Fatol
- 4,4'-Diaminophenyl Sulfone
- Diaphenylsulfone
- Dapsoderm-X
- Disulone
- Avlosulfone
- 4,4' Diaminophenyl Sulfone
-
SMILESC1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
-
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N
- Pubchem - Dapsone
- Wikipedia - dapsone
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. It is a second-line medication for the treatment and prevention of pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne, dermatitis herpetiformis, and various other skin conditions.
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Areas of Application
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Alternate Names
Estimated Properties
| Boiling Point | 355.9 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.42 g/cm3 | EPA T.E.S.T. |
| Flash Point | 261.18 C | EPA T.E.S.T. |
| Water Solubility | 78.48 mg/L | EPA T.E.S.T. |
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