Diepoxybutane (1464-53-5, 298-18-0)

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Suppliers

• Sigma-Aldrich - Diepoxybutane
  38.70 - 121.00 USD
• Fisher Scientific - Search for Diepoxybutane
• TCI - Search for Diepoxybutane

Most-cited Publications

• International Fanconi Anemia Registry: relation of clinical symptoms to diepoxybutane sensitivity (Blood, 1989)
• Fanconi anemia diagnosis and the diepoxybutane (DEB) test. (Experimental Hematology, 1993)
• The vanadium pentoxide-titanium dioxide system. Structural investigation and activity for the oxidation of butadiene (Journal of Catalysis, 1979)
• Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts (Carcinogenesis, 1994)
• Role of GSTT1and GSTM1genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes (Carcinogenesis, 1995)
• Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice (Carcinogenesis, 1994)

Areas of Application

Safety

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  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H301: Toxic if swallowed
  Danger Acute toxicity, oral - Category 3
• H314: Causes severe skin burns and eye damage
  Danger Skin corrosion/irritation - Category 1A, B, C
• H315: Causes skin irritation
  Warning Skin corrosion/irritation - Category 2
• H330: Fatal if inhaled
  Danger Acute toxicity, inhalation - Category 1, 2
• H340: May cause genetic defects
  Danger Germ cell mutagenicity - Category 1A, 1B

Trends

Alternate Names

• butadiene dioxide
• butadiene diepoxide
• erythritol anhydride, (R-(R*,R*))-isomer
• erythritol anhydride, (R*,S*)-isomer
• 1,2-3,4-diepoxybutane
• 1,2,3,4-diepoxybutane
• erythritol anhydride
• butadiene bisoxide
• 2,2'-bioxirane
• erythritol anhydride, (S-(R*,R*))-isomer
• erythritol anhydride, ((R*,R*)-(+-))-isomer
• SMILES
  C1C(O1)C2CO2
• InChIKey
  ZFIVKAOQEXOYFY-UHFFFAOYSA-N

External Links

• Pubchem - Diepoxybutane
• Wikipedia - diepoxybutane
  Diepoxybutane (also known as butane diepoxide, butadiene diepoxide, or 1,2:3,4-diepoxybutane) is a chemical compound with two epoxide functional groups. It is used as a chemical intermediate, as a curing agent for polymers, as a cross-linking agent for textiles, and as a preservative. Diepoxybutane is a carcinogen.

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Diepoxybutane

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