emodin (518-82-1)

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Suppliers

• Sigma-Aldrich - emodin
  92.40 - 321.50 USD
• Fisher Scientific - Search for emodin
• TCI - emodin
  92.00 - 543.00 USD

Most-cited Publications

• Aloe-emodin Is a New Type of Anticancer Agent with Selective Activity against Neuroectodermal Tumors (Cancer Research, 2000)
• Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. (Biochemical Pharmacology, 2005)
• Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production (Biochemical Pharmacology, 2002)
• Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9 (European Journal of Pharmacology, 2003)
• Emodin, a Protein Tyrosine Kinase Inhibitor from Polygonum cuspidatum (Journal of Natural Products, 1992)
• Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-B activation, IB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells (Oncogene, 1998)

Areas of Application

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Trends

Alternate Names

• Archin
• Frangulic Acid
• Frangula Emodin
• Rheum Emodin
• SMILES
  CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O
• InChIKey
  RHMXXJGYXNZAPX-UHFFFAOYSA-N

External Links

• Pubchem - emodin
• Wikipedia - emodin
  Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a chemical compound that can be isolated from rhubarb, buckthorn, and Japanese knotweed (Fallopia japonica syn. Polygonum cuspidatum). It is also produced by many species of fungi, including members of the genera Aspergillus, Pyrenochaeta, and Pestalotiopsis, inter alia.

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