| Weight | 318.756 g/mol |
|---|---|
| Formula | C17H15ClO4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Fenofibric acid (42017-89-0)
Score:
#1370 in Biochemistry
,
#1408 in Physics
,
#4128 in Chemistry
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- An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers (Clinical Therapeutics, 2003)
- Efficacy and safety of ABT-335 (fenofibric acid) in combination with rosuvastatin in patients with mixed dyslipidemia: A phase 3 study (Atherosclerosis, 2009)
- Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LCMS/MS with electrospray ionization: Assay development, validation and application to a clinical study (Journal of Pharmaceutical and Biomedical Analysis, 2005)
- Efficacy and safety of ABT-335 (fenofibric acid) in combination with simvastatin in patients with mixed dyslipidemia: a phase 3, randomized, controlled study. (American Heart Journal, 2009)
- Fenofibric Acid, an Active Form of Fenofibrate, Increases Apolipoprotein A-IMediated High-Density Lipoprotein Biogenesis by Enhancing Transcription of ATP-Binding Cassette Transporter A1 Gene in a Liver X ReceptorDependent Manner (Arteriosclerosis, Thrombosis, and Vascular Biology, 2005)
- Efficacy and Safety of ABT-335 (Fenofibric Acid) in Combination With Atorvastatin in Patients With Mixed Dyslipidemia (American Journal of Cardiology, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
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InChIKeyMQOBSOSZFYZQOK-UHFFFAOYSA-N
- Pubchem - Fenofibric acid
- Wikipedia - fenofibric acid
Fenofibrate, marketed as Tricor and under several other brand names, is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in people at risk of cardiovascular disease. Like other fibrates, it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density lipoprotein (HDL) levels and reducing triglyceride levels.
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Fenofibric acid
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