| Weight | 356.491 g/mol |
|---|---|
| Formula | C20H24N2O2S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
hycanthone (3105-97-3)
Score:
#854 in Biochemistry
,
#2291 in Biology
,
#2829 in Chemistry
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- Hycanthone: a frameshift mutagen. (Science, 1971)
- Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/ or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents. (Transactions of The Royal Society of Tropical Medicine and Hygiene, 1982)
- Hycanthone, a new active metabolite of lucanthone. (Journal of Medicinal Chemistry, 1967)
- Hycanthone Resistance: Development in Schistosoma mansoni (Science, 1971)
- Mutagenicity of hycanthone in mammalian cells. (Mutation Research, 1972)
- Preparation and antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone. (Journal of Medicinal Chemistry, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCN(CC)CCNC1=C2C(=C(C=C1)CO)SC3=CC=CC=C3C2=O
-
InChIKeyMFZWMTSUNYWVBU-UHFFFAOYSA-N
- Pubchem - hycanthone
- Wikipedia - hycanthone
Hycanthone is the schistosomicide approved by the FDA in 1975. It is a metabolite of lucanthone. Hycanthone interferes with parasite nerve function, resulting in paralysis and death.
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