| Weight | 504.45 g/mol |
|---|---|
| Formula | C30H16O8 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 8 |
| Rotatable Bonds | 0 |
hypericin (548-04-9)
mono-(123I)iodohypericin
Score:
#1394 in Physics
,
#3262 in Biology
,
#4074 in Chemistry
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- Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin (Proceedings of the National Academy of Sciences of the United States of America, 1988)
- Hypericin in cancer treatment: more light on the way. (The International Journal of Biochemistry & Cell Biology, 2002)
- Hypericin and its photodynamic action (Photochemistry and Photobiology, 1986)
- The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. (Journal of Biological Chemistry, 1999)
- Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity (Biochemical and Biophysical Research Communications, 1989)
- Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin (Proceedings of the National Academy of Sciences of the United States of America, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - mono-(123I)iodohypericin
-
SMILESCC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
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InChIKeyBTXNYTINYBABQR-UHFFFAOYSA-N
- Pubchem - hypericin
- Wikipedia - hypericin
Hypericin is a naphthodianthrone, an anthraquinone derivative which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine -hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.
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hypericin
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