| Weight | 285.31 g/mol |
|---|---|
| Formula | C17H11N5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
letrozole (112809-51-5)
Femara · CGS 20267 · Fmara
Score:
#354 in Biochemistry
,
#1285 in Biology
,
#1491 in Chemistry
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- A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer (The New England Journal of Medicine, 2003)
- A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. (The New England Journal of Medicine, 2005)
- Letrozole Is More Effective Neoadjuvant Endocrine Therapy Than Tamoxifen for ErbB-1 and/or ErbB-2Positive, Estrogen ReceptorPositive Primary Breast Cancer: Evidence From a Phase III Randomized Trial (Journal of Clinical Oncology, 2001)
- Randomized Trial of Letrozole Following Tamoxifen as Extended Adjuvant Therapy in Receptor-Positive Breast Cancer: Updated Findings from NCIC CTG MA.17 (Journal of the National Cancer Institute, 2005)
- Superior Efficacy of Letrozole Versus Tamoxifen as First-Line Therapy for Postmenopausal Women With Advanced Breast Cancer: Results of a Phase III Study of the International Letrozole Breast Cancer Group (Journal of Clinical Oncology, 2001)
- Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: update of study BIG 1-98 (Journal of Clinical Oncology, 2007)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Femara
- CGS 20267
- Fmara
- CGS-20267
- 4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
- Novartis Brand of Letrozole
-
SMILESC1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
-
InChIKeyHPJKCIUCZWXJDR-UHFFFAOYSA-N
- Pubchem - letrozole
- Wikipedia - letrozole
Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor which is used in the treatment of hormonally-responsive breast cancer after surgery.
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letrozole
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