Weight | 150.221 g/mol |
---|---|
Formula | C10H14O |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
Menthofuran (494-90-6)
menthofuran, (R)-isomer
Score:
#4410 in Biology
,
#5578 in Chemistry
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- Metabolic engineering of essential oil yield and composition in mint by altering expression of deoxyxylulose phosphate reductoisomerase and menthofuran synthase. (Proceedings of the National Academy of Sciences of the United States of America, 2001)
- Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase (Proceedings of the National Academy of Sciences of the United States of America, 2003)
- The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran. (Drug Metabolism and Disposition, 1987)
- A study of the monoterpene interrelationships in the genus mentha with special reference to the origin of pulegone and menthofuran (1978)
- A method of synthesis of .beta.-methylfurans and .alpha.-methylene and .beta.-methylene .gamma.-lactones. Two menthofuran syntheses (Journal of the American Chemical Society, 1977)
- Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene (Archives of Biochemistry and Biophysics, 2001)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - menthofuran, (R)-isomer
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SMILESCC1CCC2=C(C1)OC=C2C
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InChIKeyYGWKXXYGDYYFJU-UHFFFAOYSA-N
- Pubchem - Menthofuran
- Wikipedia - (+/-)-menthofuran
Menthofuran is an organic compound found in a variety of essential oils including that of Pennyroyal. It is highly toxic and believed to be the primary toxin in Pennyroyal responsible for its potentially fatal effects. After ingestion of menthofuran, it is metabolically activated to chemically reactive intermediates that are hepatotoxic.
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