| Weight | 90.082 g/mol |
|---|---|
| Formula | C2H6N2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
METHYLAZOXYMETHANOL (590-96-5)
Score:
#635 in Neuroscience
,
#2828 in Biology
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- A Neurobehavioral Systems Analysis of Adult Rats Exposed to Methylazoxymethanol Acetate on E17: Implications for the Neuropathology of Schizophrenia (Biological Psychiatry, 2006)
- Histological and neurochemical effects of fetal treatment with methylazoxymethanol on rat neocortex in adulthood. (Brain Research, 1979)
- Inhibitory effects of selenium on 1,2-dimethylhydrazine and methylazoxymethanol acetate induction of colon tumors. (Cancer Letters, 1977)
- Studies on methylazoxymethanol, the aglycone of cycasin: methylation of nucleic acids in vitro. (Biochemical Journal, 1966)
- Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. (Behavioural Brain Research, 2009)
- Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1 (Carcinogenesis, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC[N+](=NCO)[O-]
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InChIKeyBJNBRIBHKLJMAG-UHFFFAOYSA-N
- Pubchem - METHYLAZOXYMETHANOL
- Wikipedia - methylazoxymethanol
Methylazoxymethanol acetate, MAM, is a neurotoxin which reduces DNA synthesis used in making animal models of neurological diseases including schizophrenia and epilepsy. MAM is found in cycad seeds, and causes zamia staggers. It selectively targets neuroblasts in the central nervous system.
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