| Weight | 257.437 g/mol |
|---|---|
| Formula | C4H8Cl3O4P |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
Metrifonate (52-68-6)
Trichlorfon · Dipterex · Dylox
Score:
#41 in Neuroscience
,
#220 in Biology
,
#230 in Chemistry
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- Sigma-Aldrich - Metrifonate43.60 - 338.10 USD
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- Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. (Neurology, 1998)
- Metrifonate treatment of the cognitive deficits of Alzheimer's disease (Neurology, 1998)
- Physostigmine, tacrine and metrifonate: The effect of multiple doses on acetylcholine metabolism in rat brain (Neuropharmacology, 1989)
- Effect of metrifonate on extracellular brain acetylcholine and object recognition in aged rats. (European Journal of Pharmacology, 1997)
- The effects of metrifonate on the cognitive, behavioral, and functional performance of Alzheimer's disease patients (The Journal of Clinical Psychiatry, 1999)
- Evaluating response to metrifonate. (The Journal of Clinical Psychiatry, 1998)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H319: Causes serious eye irritation
Warning Serious eye damage/eye irritation - Category 2A - H340: May cause genetic defects
Danger Germ cell mutagenicity - Category 1A, 1B - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - H400: Very toxic to aquatic life
Warning Hazardous to the aquatic environment, acute hazard - Category 1 - Trichlorfon
- Dipterex
- Dylox
- Trichlorphon
- Neguvon
- Bilarcil
- Metriphonate
- Foschlor
- Chlorofos
- Chlorophos
- Ricifon
-
SMILESCOP(=O)(C(C(Cl)(Cl)Cl)O)OC
-
InChIKeyNFACJZMKEDPNKN-UHFFFAOYSA-N
- Pubchem - Metrifonate
- Wikipedia - metrifonate
Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate (DDVP). It is used as an insecticide.
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Metrifonate
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