Weight | 420.634 g/mol |
---|---|
Formula | C26H44O4 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 5 |
Obeticholic acid (459789-99-2)
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- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial (The Lancet, 2015)
- Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease (Gastroenterology, 2013)
- Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid (Gastroenterology, 2015)
- A Placebo-controlled trial of obeticholic acid in primary biliary cholangitis (The New England Journal of Medicine, 2016)
- Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats. (Hepatology, 2014)
- 28 AN INTERNATIONAL STUDY EVALUATING THE FARNESOID X RECEPTOR AGONIST OBETICHOLIC ACID AS MONOTHERAPY IN PBC (Journal of Hepatology, 2011)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)C)O
-
InChIKeyZXERDUOLZKYMJM-UHFFFAOYSA-N
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