Weight | 244.29 g/mol |
---|---|
Formula | C15H16O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
Osthole (484-12-8)
Score:
#1074 in Neuroscience
,
#2346 in Biochemistry
,
#4654 in Biology
,
#5907 in Chemistry
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- Sigma-Aldrich - Osthole111.00 - 411.00 USD
- Fisher Scientific - Search for Osthole
- TCI - Osthole84.00 - 882.00 USD
- Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cells. (Journal of Pharmacology and Experimental Therapeutics, 2005)
- Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study (Epilepsy Research, 2009)
- Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway (Journal of Experimental & Clinical Cancer Research, 2011)
- Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats (Brain Research, 2010)
- Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway. (Neuroscience, 2011)
- Osthole regulates inflammatory mediator expression through modulating NF-B, mitogen-activated protein kinases, protein kinase C, and reactive oxygen species. (Journal of Agricultural and Food Chemistry, 2010)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
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InChIKeyMBRLOUHOWLUMFF-UHFFFAOYSA-N
- Pubchem - Osthole
- Wikipedia - osthol
Osthol is an O-methylated coumarin. It is a calcium channel blocker, found in plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.
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