Weight | 174.196 g/mol |
---|---|
Formula | C7H7FO2S |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
Phenylmethylsulfonyl fluoride (329-98-6)
Phenylmethanesulfonyl Fluoride · Benzenemethanesulfonyl Fluoride
Score:
#78 in Molecular and cellular biology
,
#2199 in Biochemistry
,
#4468 in Biology
,
#5657 in Chemistry
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- A rapid method for the purification of bovine thrombin and the inhibition of the purified enzyme wtih phenylmethylsulfonyl fluoride. (Biochemistry, 1971)
- Inactivation of the protease inhibitor phenylmethylsulfonyl fluoride in buffers (Analytical Biochemistry, 1978)
- Chemical modification of papain: I. Reaction with the chloromethyl ketones of phenylalanine and lysine and with phenylmethylsulfonyl fluoride (Archives of Biochemistry and Biophysics, 1968)
- Promotion of organophosphate-induced delayed polyneuropathy by phenylmethanesulfonyl fluoride. (Toxicology and Applied Pharmacology, 1991)
- Potentiation of organophosphorusinduced delayed neurotoxicity by phenylmethylsulfonyl fluoride (Journal of Toxicology and Environmental Health, 1990)
- The Effect of the Enzyme Inhibitor Phenylmethylsulfonyl Fluoride on the Pharmacological Effect of Anandamide in the Mouse Model of Cannabimimetic Activity (Journal of Pharmacology and Experimental Therapeutics, 1997)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Phenylmethanesulfonyl Fluoride
- Benzenemethanesulfonyl Fluoride
-
SMILESC1=CC=C(C=C1)CS(=O)(=O)F
-
InChIKeyYBYRMVIVWMBXKQ-UHFFFAOYSA-N
- Pubchem - Phenylmethylsulfonyl fluoride
- Wikipedia - phenylmethanesulfonyl fluoride
In biochemistry, phenylmethane sulfonyl fluoride or phenylmethylsulfonyl fluoride (PMSF) is a serine protease inhibitor commonly used in the preparation of cell lysates. PMSF does not inhibit all serine proteases. It is rapidly degraded in water and stock solutions are usually made up in anhydrous ethanol, isopropanol, corn oil, or DMSO.
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