Weight | 192.262 g/mol |
---|---|
Formula | C11H16N2O |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
Pozanicline (161417-20-5, 161417-03-4)
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- Pozanicline for the treatment of attention-deficit/hyperactivity disorder (Expert Opinion on Investigational Drugs, 2014)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C=CC=N1)OCC2CCCN2
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InChIKeyYRVIKLBSVVNSHF-UHFFFAOYSA-N
- Pubchem - Pozanicline
- Wikipedia - pozanicline
Pozanicline (INN, codenamed ABT-089) is a drug developed by Abbott, that has nootropic and neuroprotective effects. Animal studies suggested it useful for the treatment of ADHD and subsequent human trials have shown ABT-089 to be effective for this application. It binds with high affinity subtype-selective to the 42 nicotinic acetylcholine receptors and has partial agonism to the 62 subtype, but not the 7 and 34 subtypes familiar to nicotine.
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