| Weight | 166.196 g/mol |
|---|---|
| Formula | C8H15NaO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
Sodium valproate (1069-66-5)
Valproic Acid · Valproate · Divalproex
Score:
#6 in Neuroscience
,
#40 in Biology
,
#41 in Chemistry
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- Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells (The EMBO Journal, 2001)
- Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen (Journal of Biological Chemistry, 2001)
- A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized TonicClonic Seizures in Adults (The New England Journal of Medicine, 1992)
- Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy (The New England Journal of Medicine, 1993)
- The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. (The Lancet, 2007)
- The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS (Journal of Neurochemistry, 1999)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H362: May cause harm to breast-fed children
Reproductive toxicity, effects on or via lactation - Additional category - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - Valproic Acid
- Valproate
- Divalproex
- Depakote
- Depakene
- Divalproex Sodium
- Valproate Sodium
- Depakine
- 2 Propylpentanoic Acid
- 2-Propylpentanoic Acid
- Valproate Calcium
- Dipropyl Acetate
- Propylisopropylacetic Acid
- Calcium Valproate
- Convulsofin
- Valproic Acid, Sodium Salt (2:1)
- Ergenyl
- Vupral
- Magnesium Valproate
- Semisodium Valproate
-
SMILESCCCC(CCC)C(=O)[O-].[Na+]
-
InChIKeyAEQFSUDEHCCHBT-UHFFFAOYSA-M
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Sodium valproate
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