| Weight | 234.73 g/mol |
|---|---|
| Formula | C13H15ClN2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
Tacrine hydrochloride (1684-40-8)
THA · Tacrine · Cognex
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- A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease (JAMA, 1994)
- A Double-Blind, Placebo-Controlled Multicenter Study of Tacrine for Alzheimer's Disease (The New England Journal of Medicine, 1992)
- A Controlled Trial of Tacrine in Alzheimer's Disease (JAMA, 1992)
- Hepatotoxic Effects of Tacrine Administration in Patients With Alzheimer's Disease (JAMA, 1994)
- A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. (JAMA, 1994)
- TACRINE IN ALZHEIMER'S DISEASE (The Lancet, 1991)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - THA
- Tacrine
- Cognex
- Tetrahydroaminoacridine
- 9-Amino-1,2,3,4-Tetrahydroacridine
- Parke Davis Brand of Tacrine Hydrochloride
- 1,2,3,4-Tetrahydroaminoacridine
- Tenakrin
- Horizon Brand of Tacrine Hydrochloride
- Woods Brand of Tacrine Hydrochloride
- 1,2,3,4-Tetrahydro-9-acridinamine
- Romotal
- OTL Pharm Brand of Tacrine Hydrochloride
-
SMILESC1CCC2=NC3=CC=CC=C3C(=C2C1)N.Cl
-
InChIKeyZUFVXZVXEJHHBN-UHFFFAOYSA-N
- Pubchem - Tacrine hydrochloride
- Wikipedia - tacrine hydrochloride
Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist (parasympathomimetic). It was the first centrally acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease, and was marketed under the trade name Cognex. Tacrine was first synthesised by Adrien Albert at the University of Sydney.
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